![]() ![]() Furthermore, we demonstrated the requirement of the PopP2 EAR motif for PTIĪdrian Marino and the intellectual travel journal as an expression of revolutionary freedomįull Text Available Seen as a logical continuation of the author’s preoccupations for comparative literature, the travel journal becomes a journal of ideas in Adrian Marino’s case, by trying not only to explain the formation of a certain type of personality, but also to transcribe/redact a chronicle of social and political history. We show that the EAR motif-dependent gain of avirulence correlated with the stability of the PopP2 protein. This lack of recognition was partially but significantly reverted by the C-terminal addition of a synthetic EAR motif. Remarkably, mutation of the EAR motif disabled PopP2 avirulence function as measured by the development of hypersensitive response, electrolyte leakage, defense marker gene expression and bacterial growth in Arabidopsis. We also found that PopP2 harbors a putative eukaryotic transcriptional repressor motif (ethylene-responsive element binding factor-associated amphiphilic repression or EAR, which is known to be involved in the recruitment of transcriptional co-repressors. Only one variation (a premature stop codon caused the loss of RPS4/RRS1-dependent recognition in Arabidopsis. Our analysis revealed high conservation of popP2 sequence with only three polymorphic alleles present amongst 17 strains. solanacearum strains isolated from diseased tomato and pepper fields across the Republic of Korea. Here, we surveyed the naturally occurring variation in PopP2 sequence among the R. PopP2 is an acetyltransferase that binds to and acetylates the RRS1 WRKY DNA-binding domain resulting in reduced RRS1-DNA association thereby activating plant immunity. solanacearum effector PopP2 in the nuclei of infected cells. In the model species Arabidopsis thaliana, the paired immune receptors RRS1 (resistance to Ralstonia solanacearum 1 and RPS4 (resistance to Pseudomonas syringae 4 cooperatively recognize the R. Plants have, however, evolved specialized immune receptors that recognize corresponding effectors and confer qualitative disease resistance. solanacearum secretes around 70 effectors into host cells in order to promote infection. During his career he enjoyed many summers working in the United States.Ī Conserved EAR Motif Is Required for Avirulence and Stability of the Ralstonia solanacearum Effector PopP2 In Plantaĭirectory of Open Access Journals (Sweden)įull Text Available Ralstonia solanacearum is the causal agent of the devastating bacterial wilt disease in many high value Solanaceae crops. ![]() ![]() In 1984, he left Cambridge to become director and cofounder of the Hooke Institute in Oxford, U.K. After a year at the Massachusetts Institute of Technology (Cambridge, Mass.), he returned to Cambridge in Britain, where he spent most of the rest of his life. at Cambridge University, Cambridge, U.K., in 1963. My sadness and disbelief are more strongly felt because the life of this gifted and generous man ended so early.Born in Melbourne, Australia, Adrian was granted his Ph.D. On April 19, Adrian Gill, FRS, my former thesis advisor and distinguished friend, died suddenly of cancer. 1935), kes töötas 1970-ndate lõpul ja 1980-ndate alguses telefoni, faksi ja varaste kirjakstisüsteemidega kunstiprojektide kallal, osales 1970-ndate ja 1980-ndate multimeediaprojektides aastast Viinis elava kanada kunstniku Robert Adrian X-ga (sünd. Robert Adrian X / Robert Adrian X interv. Wenninger in front of one of eight 25-metre-long aluminium-alloy coil casings that will house the racetrack coils of the barrel toroid magnet system. Wenninger in front of one of the two vacuum vessels for the ATLAS end-cap toroid magnets.Photo 02: Prof. Popp is pictured here in the ATLAS detector assembly hall with Dr. Manfred Popp, Chairman of the Executive Board, Forschungszentrum Karlsruhe GmbH
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